HPLC Determination of Valacyclovir on Primesep 100 Column

HPLC Method for Valacyclovir on Primesep 100 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Valacyclovir

Valacyclovir belongs to a class of drugs called antiviral drugs and has the chemical formula C13H20N6O4. Valacyclovir is used to treat viral infections caused by a group of viruses called herpes simplex viruses. These infections include oral and genital herpes as well as shingles. It can also be used to treat chickenpox in children.

Valacyclovir can be retained on a Valacyclovir mixed-mode column with great peak shape using an isocratic method of acetonitrile (ACN), water and sulfuric acid (H2SO4) as a buffer. UV Detection 255nm.

Condition
Column Primesep 100, 3.2 x 100 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 30/70%
Buffer H2SO4 – 0.2%
Flow Rate 0.5 ml/min
Detection UV, 255 nm

 

Description
Class of Compounds
 Drug
Analyzing Compounds Valacyclovir

 

Application Column

Primesep 100

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Valacyclovir
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.