Perindopril is an ACE inhibitor used in treating hypertension (high blood pressure). It comes in tablet form. Perindopril can be retained on a Primesep 200 column in under 8 minutes with a simple isocratic mobile phase and sulphuric acid buffer. Primesep 200 is a reverse-phase (RP) mixed-mode column with embedded weak acidic ion-pairing groups
Condition
Column Primesep 200, 4.6×150 mm, 5 µm, 100A Mobile Phase MeCN/H2O – 20/80% Buffer H2SO4 – 0.4 % Flow Rate 1.0 ml/min Detection UV, 205 nm
Description
Class of Compounds
Drug, Acid, Hydrophobic, Ionizable Analyzing Compounds Perindopril
Application Column
Primesep 200
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
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