HPLC Method for Analysis of 4-(2-Aminoethyl) benzenesulfonamide on Primesep 100 by SIELC Technologies
Separation type: Liquid Chromatography Mixed-mode
4-(2-Aminoethyl) benzenesulfonamide, when combined with hypoxic conditions, can inhibit the growth and induce apoptosis of human hepatocellular carcinoma cells. This Benzenesulfonamide can be retained and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple mobile phase of water, Acetonitrile (MeCN), and a Sulfuric acid (H2SO4) buffer. This analysis method can be detected in the low UV regime at 220 nm.
High Performance Liquid Chromatography (HPLC) Method for Analysis of 4-(2-Aminoethyl) benzenesulfonamide
Condition
Column | Primesep 100, 4.6×150 mm, 5 µm, 100A |
Mobile Phase | MeCN/H2O – 20/80% |
Buffer | H2SO4 – 0.2% |
Flow Rate | 1.0 ml/min |
Detection | UV 220, 265 nm |
Peak Retention Time | 5.21 min |
Description
Class of Compounds | Amide |
Analyzing Compounds | 4-(2-Aminoethyl) benzenesulfonamide |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A