Valsartan is a nonpeptide triazole-derived antagonist of angiotensin that selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor. It is used to treat high blood pressure and heart failure, as well as to improve the chance of someone living longer after a heart attack. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Valsartan. The method is UV compatible and can be used as a general approach for analyzing similar compounds.
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