Cortisol (hydrocortisone) is a steroid hormone produced by the adrenal gland. Hydrocortisone is a hydrophobic neutral compound with some polar groups in its structure. Several Primesep mixed-mode columns were used for separation of hydrocortisone and its degradation products. Each column showed a different selectivity for separation, which attributed to different polar-embedded groups on Primesep 100 and Primesep D columns. Both columns can be used for degradation studies of various hydrophobic compounds.
Application Column
Primesep 100
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options
Primesep D
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select optionsHydrocortisone
