| CAS Number | 1124-64-7 |
|---|---|
| Molecular Formula | C9H14ClN |
| Molecular Weight | 171.67 |
| InChI Key | POKOASTYJWUQJG-UHFFFAOYSA-M |
| Synonyms |
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Applications:
HPLC Method for Analysis of 1-Butylpyridinium Chloride on Newcrom AH Column
July 12, 2023
Separation type: Liquid Chromatography Mixed-mode
HPLC Method for Analysis of 1-Butylpyridinium Chloride on Newcrom AH by SIELC Technologies
1-Butylpyridinium chloride is a type of ionic liquid. An ionic liquid is a salt in which the ions are poorly coordinated, and at least one ion has a delocalized charge. One component is organic, which prevents the formation of a stable crystal lattice, so these substances are often liquid at room temperature.
In 1-Butylpyridinium chloride, the cation is a butylpyridinium ion, a pyridine ring (a six-membered aromatic ring with five carbon atoms and one nitrogen atom) with a butyl group (four carbon alkyl chain) attached. The anion is chloride (Cl-).
Ionic liquids, including 1-Butylpyridinium chloride, have various applications in fields such as electrochemistry, catalysis, and as solvents for a variety of chemical reactions. Their properties, like their melting point, viscosity, and solvation potential, can be adjusted by choosing different cations and anions, which makes them very versatile.
The 1-Butylpyridinium chloride can be retained, analyzed, on a Newcrom AH column using an isocratic analytical method with a simple mobile phase of water, Acetonitrile (MeCN), and an Ammonium formate (AmFm) ionic modifier. This analysis method can be detected with an Evaporative Light Scattering Detector (ELSD) or any other evaporative detection method (CAD, ESI-MS).
LOD was determined for this combination of instrument, method, and analyte, and it can vary from one laboratory to another even when the same general type of analysis is being performed.
High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Butylpyridinium Chloride
Condition
| Column | Newcrom AH, 4.6 x 100 mm, 5 µm, 100 A |
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | AmFm pH 3.0- 10 mM |
| Flow Rate | 1.0 ml/min |
| Detection | ELSD, the nebulizer and evaporator temperatures 50 °C, with a gas flow rate of 1.6 Standard Liters per Minute (SLM) (MS- compatible mobile phase) |
| Peak Retention Time | 7.12 min |
| Sample concentration | 0.3 mg/ml |
| Injection volume | 1 µl |
| LOD | UV- 30 ppb, ELSD – 70 ppb |
Description
| Class of Compounds | Pyridinium salts |
| Analyzing Compounds | 1-Butylpyridinium Chloride |
Application Column
Newcrom AH
Column Diameter: 4.6 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
HPLC Method for Separation of 1-Butylpyridinium chloride and 1-Ethylpyridinium bromide on Newcrom AH Column
July 12, 2023
HPLC Method for Separation of 1-Ethylpyridinium bromide, 1-Butylpyridinium Chloride on Newcrom AH by SIELC Technologies
Separation type: Liquid Chromatography Mixed-mode
1-Butylpyridinium chloride and 1-Ethylpyridinium bromide are types of ionic liquids. Ionic liquids are salts in which the ions are poorly coordinated, which results in these solvents being liquid below 100°C, or even at room temperature (ambient temperature). At least one ion has a delocalized charge and one component is organic, which prevents the formation of a stable crystal lattice.
1-Butylpyridinium chloride has a butyl group attached to a pyridinium ring, and its counterion is chloride (Cl-).
1-Ethylpyridinium bromide, on the other hand, has an ethyl group attached to a pyridinium ring, and its counterion is bromide (Br-).
These compounds are part of a larger class of pyridinium-based ionic liquids. They have various applications, including in electrochemistry, organic synthesis, and as solvents for polymers. Like other ionic liquids, their properties (such as melting point, viscosity, and solvation potential) can be adjusted by selecting different counterions or changing the groups attached to the pyridinium ring.
1-Butylpyridinium chloride and 1-Ethylpyridinium bromide,” belong to a class of compounds known as pyridinium salts. These compounds are derived from the parent compound pyridine, which is a six-membered aromatic ring containing one nitrogen atom.
These pyridinium salts often have unique physical and chemical properties due to the presence of the charged pyridinium cation. They are commonly used in various applications, including as catalysts, ionic liquids, and electrolytes in electrochemical systems. The specific properties and applications of these compounds can vary depending on the nature of the alkyl group and the anion associated with the pyridinium cation
Both compounds can be retained, separated, and analyzed, on a Newcrom AH column using an isocratic analytical method with a simple mobile phase of water, Acetonitrile (MeCN), and an Ammonium formate (AmFm) ionic modifier. This analysis method can be detected with an Evaporative Light Scattering Detector (ELSD) or any other evaporative detection method (CAD, ESI-MS).
High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Ethylpyridinium bromide, 1-Butylpyridinium Chloride
Condition
| Column | Newcrom AH, 4.6 x 100 mm, 5 µm, 100 A |
| Mobile Phase | Gradient MeCN/H2O – 30-80%, 10 min |
| Buffer | AmFm pH 3.0- 10 mM |
| Flow Rate | 1.0 ml/min |
| Detection | ELSD, the nebulizer and evaporator temperatures 50 °C, with a gas flow rate of 1.6 Standard Liters per Minute (SLM) (MS- compatible mobile phase) |
| Peak Retention Time | 5.12, 7.18 min |
| Sample concentration | 0.3 mg/ml |
| Injection volume | 1µl |
| LOD | UV- 30 ppb, ELSD – 70 ppb |
Description
| Class of Compounds | Pyridinium salts |
| Analyzing Compounds | 1-Ethylpyridinium bromide, 1-Butylpyridinium Chloride |
Application Column
Newcrom AH
Column Diameter: 4.6 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
1-Ethylpyridinium bromide
