| CAS Number | 106-51-4 |
|---|---|
| Molecular Formula | C6H4O2 |
| Molecular Weight | 108.097 |
| InChI Key | AZQWKYJCGOJGHM-UHFFFAOYSA-N |
| LogP | 0.2 |
| Synonyms |
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Applications:
HPLC Separation of Haloaromatics and Quinones on Newcrom B Column
February 6, 2020
| Column | Newcrom B, 4.6×150 mm, 3 µm, 100A |
| Mobile Phase | MeCN/H2O – 55/45% |
| Buffer | H3PO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 200 nm |
| Class of Compounds | Haloaromatics, Quinones, Hydrophobic |
| Analyzing Compounds | 1,4-benzoquinone, 1,4-hydroquinone, Chloranil (Tetrachloro-1,4-benzoquinone), Chlorothalonil, Tetrachlorohydroquinone, Pentachlorophenol |
Application Column
Newcrom B
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsChloranil
Chlorothalonil
Hydroquinone
Pentachlorophenol
Tetrachlorohydroquinone
Dewetting Study in Aqueous Conditions
September 18, 2003
Most reversed-phase HPLC columns, such as C18, are incompatible with 100% aqueous mobile phases due to dewetting (collapse) of the stationary phase. Primesep columns combine reversed-phase with polar functional groups which eliminate the problems of dewetting. The Primesep 100 column in this application with an acetonitrile (MeCN, ACN) shows a retention time of 2.5 minutes. In 100% water, the retention time is 3 minutes even after sitting 24 hours in the water mobile phase. On a C18 phase, the analyte retention would have been lost and elution at the void (1.5 minutes) would have resulted.
| Column | Primesep 100 |
| Mobile Phase | MeCN/H2O |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 270 nm |
Application Column
Primesep 100
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options
Primesep C
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options
