Trimazosin hydrochloride anhydrous

Trimazosin hydrochloride anhydrous structural formula

CAS Number35795-17-6
Molecular FormulaC20H30ClN5O6
Molecular Weight471.941
InChI KeyKJZWJYNJYOFTNQ-UHFFFAOYSA-N
LogP0.831
Synonyms
  • Trimazosin hydrochloride anhydrous
  • 2-Hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate--hydrogen chloride (1/1)
  • 1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, hydrochloride (1:1)
  • 35795-17-6
  • EINECS 252-733-2
  • NSC 355084
  • UNII-OT29P74170

Applications:

Separation of Trimazosin hydrochloride anhydrous on Newcrom R1 HPLC column

May 16, 2018
Separation of Trimazosin hydrochloride anhydrous on Newcrom R1 HPLC column

Trimazosin hydrochloride anhydrous can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Trimazosin hydrochloride anhydrous
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.