Thiodiglycolic acid

Thiodiglycolic acid structural formula

CAS Number123-93-3
Molecular FormulaC4H6O4S
Molecular Weight150.150
InChI KeyUVZICZIVKIMRNE-UHFFFAOYSA-N
LogP-0.436
Synonyms
  • Thiodiglycolic acid
  • 2,2'-Sulfanediyldiacetic acid
  • Acetic acid, 2,2'-thiobis-
  • 123-93-3
  • 4-03-00-00612
  • BRN 1764392
  • (Carboxymethylthio)acetic acid
  • Dimethylsulfide-alpha-alpha'-dicarboxylic acid
  • EINECS 204-663-9
  • NSC 28743
  • UNII-483M3RG5GW
  • 2,2'-Thiodiacetic acid
  • 2,2'-Thiodiglycolic acid
  • 2,2'-thiobisacetic acid
  • 2,2'-thiodiethanoic acid
  • 2-[(carboxymethyl)sulfanyl]acetic acid
  • Mercaptodiacetic acid
  • TDGA
  • Thiodiacetic acid
  • Thiodiglycollic acid
  • Usaf cb-36
  • Usaf e-2
  • alpha,alpha'-Dicarboxylic acid
  • dicarboxymethyl sulfide
  • thiodi(acetic acid)

Applications:

Separation of Thiodiglycolic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Thiodiglycolic acid on Newcrom C18 HPLC column

Thiodiglycolic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Thiodiglycolic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.