Sodium valproate

Sodium valproate structural formula

CAS Number1069-66-5
Molecular FormulaC8H15NaO2
Molecular Weight166.196
InChI KeyAEQFSUDEHCCHBT-UHFFFAOYSA-M
LogP1.90
Synonyms
  • Sodium valproate
  • Sodium 2-propylpentanoate
  • Pentanoic acid, 2-propyl-, sodium salt (1:1)
  • 1069-66-5
  • Pentanoic acid, 2-propyl-, sodium salt
  • Acediprol
  • Convulex
  • Depacon
  • Depakene
  • Depakene R
  • Depakene syrup 8
  • Depakin
  • Depakine chronosphere
  • Dipropylacetate sodium
  • Micropakine LP
  • Natriumvalproat
  • Orfiril
  • Pentanoic acid, 2-propyl-, sodium salt (1:1)
  • Selenica R
  • Sodium 2-propylpentanoate
  • Sodium 2-propylvalerate
  • Sodium bispropylacetate
  • Sodium dipropylacetate
  • Sodium ?,?-dipropylacetate
  • Valeric acid, 2-propyl-, sodium salt
  • Valerin
  • valproate de sodium
  • Valproate sodium
  • valproato de sodio
  • Valpron
  • EINECS 213-961-8
  • Eurekene
  • Labazene
  • 2-Propylpentanoic acid sodium salt
  • 2-Propylvaleric acid sodium salt
  • Sodium n-dipropylacetate
  • Sodium 2-n-propyl-pentanoate
  • Valproic acid sodium salt
  • Natrium valproat
  • Valproinsaeure, natrium
  • Valproic acid sodium salt (1:1)
  • UNII-5VOM6GYJ0D
  • Epilim

Applications:

Separation of Sodium valproate on Newcrom R1 HPLC column

February 16, 2018
Separation of Sodium valproate on Newcrom C18 HPLC column

Sodium valproate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Sodium valproate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.