Sodium deoxycholate

Sodium deoxycholate structural formula

CAS Number302-95-4
Molecular FormulaC24H39NaO4
Molecular Weight414.563
InChI KeyFHHPUSMSKHSNKW-SMOYURAASA-M
LogP3.39
Synonyms
  • Sodium deoxycholate
  • Sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate
  • Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt, (3alpha,5beta,12alpha)- (1:1)
  • 302-95-4
  • Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3?,5?,12?)-
  • 3,12-Dihydroxycholan-24-oic acid sodium salt
  • 3?,12?-Dihydroxy-5?-cholan-24-oate de sodium
  • 3-?,12-?-dihydroxy-5-?-cholane-24-oate de sodium
  • 3-?-12-?-dihidroxi-5-?-colan-24-oato de sodio
  • 5?-Cholan-24-oic acid, 3?,12?-dihydroxy-, monosodium salt
  • Deoxycholic acid monosodium salt
  • Deoxycholic acid sodium salt
  • Desoxycholate sodium
  • Desoxycholic acid sodium salt
  • Natrium-3-?,12-?-dihydroxy-5-?-cholan-24-oat
  • NSC 681065
  • sodium 3-?,12-?-dihydroxy-5-?-cholan-24-oate
  • Sodium 3?,12?-dihydroxy-5?-cholanate
  • Sodium 7-deoxycholate
  • Sodium desoxycholate
  • 3-alpha,12-alpha-Dihydroxy-5-beta-cholan-24-oic acid sodium salt
  • EINECS 206-132-7
  • Sodium deoxycholic acid
  • Dihydroxy 3-12 cholanate de Na
  • Na-Desoxycholat
  • Natrium-3-alpha,12-alpha-dihydroxycholanat
  • UNII-436LS6U35Y
  • deoxycholate sodium
  • 98805-61-9

Applications:

Separation of Sodium deoxycholate on Newcrom R1 HPLC column

February 16, 2018
Separation of Sodium deoxycholate on Newcrom C18 HPLC column

Sodium deoxycholate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Sodium deoxycholate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.