HPLC Method for Analysis of Propofol on Newcrom R1 Column

Propofol is an anesthetic agent used in maintenance of general anesthesia and procedural sedation. The drug has a very short recovery period of a couple of minutes, but the side effects include an irregular heart rate, low blood pressure, and possibly the stopping of breathing.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Propofol
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