Scopolamine methylbromide

Scopolamine methylbromide structural formula

CAS Number155-41-9
Molecular FormulaC18H24BrNO4
Molecular Weight398.297
  • Scopolamine methylbromide
  • (1R,2R,4S,5S,7s)-7-{[(2S)-3-Hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[,4~]nonan-9-ium bromide
  • 3-Oxa-9-azoniatricyclo[,4~]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1R,2R,4S,5S)- (1:1)
  • 155-41-9
  • 3-Oxa-9-azoniatricyclo[,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1?,2?,4?,5?,7?)-
  • (-)-Scopolamine methobromide
  • (-)-Scopolamine methyl bromide
  • 1?H,5?H-Tropanium, 6?,7?-epoxy-3?-hydroxy-8-methyl-, bromide, (-)-tropate
  • 3-Oxa-9-azoniatricyclo[,4]nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-, bromide, [7(S)-(1?,2?,4?,5?,7.beta]).-
  • 3-Oxa-9-azoniatricyclo[,4]nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-, bromide, [7(S)-(1?,2?,4?,5?,7?)]-
  • 3-Oxa-9-azoniatricyclo[,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide (1:1), (1?,2?,4?,5?,7?)-
  • Ampyrox
  • Bromure de N-methylhyoscinium
  • bromuro de N-metilhioscinio
  • Epoxymethamine bromide
  • Epoxytropine tropate methylbromide
  • Holopon
  • Hyoscine methobromide
  • Hyoscine methyl bromide
  • Lescopine bromide
  • Mescopil
  • Methscopolamin bromide
  • Methscopolamine bromide
  • Methylscopolamine bromide
  • Neo-Avagal
  • N-methylhyoscinium bromide
  • N-Methylhyosciniumbromid
  • N-Methylscopolamine bromide
  • N-Methylscopolammonium bromide
  • NSC 120606
  • NSC 61809
  • Pamine bromide
  • Paraspan
  • Proscomide
  • Restropin
  • Scopolamine methobromide
  • Scopolamine methyl bromide
  • EINECS 205-844-5
  • 6beta,7beta-Epoxy-3alpha-hydroxy-8-methyl-1alphaH,5alphaH-tropanium bromide (-)-tropate
  • 7-(3-Hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-3-oxo-9-azoniatricyclo-(,4))nonane bromide
  • Hyoscine methylbromide
  • Methoscopylamine bromide
  • Methylscopolamine hydrobromide
  • Scopolammonium, N-methyl-, bromide
  • Scopolammonium, N-methylbromide
  • 1alphaH,5alphaH-Tropanium, 6beta,7beta-epoxy-3alpha-hydroxy-8-methyl-, bromide, (-)-tropate
  • 1-alpha-H,5-alpha-H-Tropanium,6-beta,7-beta-epoxy-3-alpha-hydroxy-8-methyl-, bromide,
  • Scordin
  • (S)-6beta,7beta-Epoxy-8-methyl-3alpha-(-)-tropoyloxy-1alphaH,5alphaH-tromanium bromide
  • Hyoscin methobromide
  • Hyoscin-N-methylbromid
  • Scopolamin-N-methylbromid
  • Pamine Forte
  • (-)-(1S,3s,5R,6R,7S)-6,7-epoxy-8-methyl-3-[(S)-tropoyloxy]tropanium bromide
  • (S)-6beta,7beta-epoxy-8-methyl-3alpha-(-)-tropoyloxy-1alphaH,5alphaH-tromanium bromide
  • N-methylhyoscine bromide
  • 1420-31-1
  • 2660-04-0


Separation of Scopolamine methylbromide on Newcrom R1 HPLC column

February 16, 2018
Separation of Scopolamine methylbromide on Newcrom C18 HPLC column

Scopolamine methylbromide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Scopolamine methylbromide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.