Prednisolone acetate

Prednisolone acetate structural formula

CAS Number52-21-1
Molecular FormulaC23H30O6
Molecular Weight402.487
InChI KeyLRJOMUJRLNCICJ-JZYPGELDSA-N
LogP2.40
Synonyms
  • Prednisolone acetate
  • (11beta)-11,17-Dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11beta)-
  • 52-21-1
  • Pregna-?1,?4-?diene-?3,?20-?dione, 21-?(acetyloxy)?-?11,?17-?dihydroxy-?, (11beta)?-
  • Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-acetate
  • (11beta)-21-(Acetyloxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione
  • 11beta,17alpha,21-Trihydroxypregna-1,4-diene-3,20-dione 21-acetate
  • 21-(Acetoxy)-11beta,17alpha-dihydroxypregna-1,4-diene-3,20-dione
  • 21-Acetoxy-11beta,17-dihydroxypregna-1,4-diene-3,20-dione
  • Meticotelone acetate
  • Prednisolone 21-acetate
  • Hydroprednisone acetate
  • 21-acetato de prednisolona
  • Prednisolon-21-acetat
  • 21-Acetate de prednisolone
  • 4-08-00-03468
  • BRN 3111798
  • Cormalone
  • Cortipred
  • Deltilen
  • Durapred
  • Econopred
  • EINECS 200-134-1
  • Meticortelone acetate
  • Nisolone
  • NSC 10966
  • Pred Forte
  • Pred Mild
  • Prediacortine
  • Predicort
  • Prednelan-N
  • Prednidoren
  • Predonine injection
  • Prenema
  • Pricortin
  • Supercortyl
  • Omnipred
  • Flo-Pred
  • UNII-8B2807733D

Applications:

Separation of Prednisolone acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Prednisolone acetate on Newcrom C18 HPLC column

Prednisolone acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Prednisolone acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.