Oxaprozin

Oxaprozin structural formula

CAS Number21256-18-8
Molecular FormulaC18H15NO3
Molecular Weight293.322
InChI KeyOFPXSFXSNFPTHF-UHFFFAOYSA-N
LogP4.19
Synonyms
  • Oxaprozin
  • 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
  • 2-Oxazolepropanoic acid, 4,5-diphenyl-
  • 21256-18-8
  • 2-Oxazolepropanoic acid, 4,5-diphenyl-
  • 2-Oxazolepropionic acid, 4,5-diphenyl-
  • 3-(4,5-Diphenyloxazol-2-yl)propionic acid
  • 4,5-Diphenyl-2-oxazolepropionic acid
  • Actirin
  • Durapro
  • Duraprost
  • NSC 310839
  • oxaprozina
  • oxaprozine
  • ?-(4,5-Diphenyloxazol-2-yl)propionic acid
  • BRN 1083168
  • 4,5-Diphenyl-2-oxazolepropanoic acid
  • 3-(4,5-Diphenyl-2-oxazolyl)propenoic acid
  • beta-(4,5-Diphenyloxazol-2-yl)propionic acid
  • EINECS 244-296-1
  • Oxaprozinum
  • UNII-MHJ80W9LRB

Applications:

Separation of Oxaprozin on Newcrom R1 HPLC column

February 16, 2018
Separation of Oxaprozin on Newcrom C18 HPLC column

Oxaprozin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Oxaprozin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.