Olsalazine

Olsalazine structural formula

CAS Number15722-48-2
Molecular FormulaC14H10N2O6
Molecular Weight302.243
InChI KeyQQBDLJCYGRGAKP-UHFFFAOYSA-N
LogP3.73
Synonyms
  • Olsalazine
  • 3,3'-Diazenediylbis(6-hydroxybenzoic acid)
  • Benzoic acid, 3,3'-(1,2-diazenediyl)bis[6-hydroxy-
  • 15722-48-2
  • Benzoic acid, 3,3'-azobis[6-hydroxy-
  • 3,3'-Azobis(6-hydroxybenzoic acid)
  • 3,3'-Dicarboxy-4,4'-dihydroxyazobenzene
  • 5,5'-Azobis(salicylic acid)
  • 5,5'-Azodisalicylic acid
  • Azodisal
  • Benzoic acid, 3,3'-(1,2-diazenediyl)bis[6-hydroxy-
  • C.I. Mordant Yellow 5
  • Salicylic acid, 5,5'-azodi-
  • Dipentium
  • UNII-ULS5I8J03O
  • Olsalazina
  • Olsalazinum

Applications:

HPLC Method for Analysis of Olsalazine on Newcrom R1 Column

July 12, 2022
Separation type: Liquid Chromatography Reverse Phase
 

 
 

HPLC Method for Analysis of Olsalazine on Newcrom R1 Column
High Performance Liquid Chromatography (HPLC) Method for Analysis of Olsalazine

Condition
Column Newcrom R1, 2.1×100 mm, 3 µm, 100A
Mobile Phase MeCN – 50%
Buffer H2SO4 – 0.2
Flow Rate 1.0 ml/min
Detection UV 224 nm

 

Description
Class of Compounds
 Drug
Analyzing Compounds Olsalazine

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Olsalazine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Olsalazine on Newcrom R1 HPLC column

May 16, 2018
Separation of Olsalazine on Newcrom R1 HPLC column

Olsalazine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Olsalazine
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.