N2-D-Gluconoyl-N5-((D-gluconoylamino)iminomethyl)-L-ornithine structural formula

CAS Number94071-05-3
Molecular FormulaC18H34N4O14
Molecular Weight530.481
  • N2-D-Gluconoyl-N5-((D-gluconoylamino)iminomethyl)-L-ornithine
  • (2S)-2-{[(2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoyl]amino}-5-[(E)-({2-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]hydrazinyl}methylidene)amino]pentanoic acid (non-preferred name)
  • 94071-05-3
  • EINECS 301-805-2


Separation of N2-D-Gluconoyl-N5-((D-gluconoylamino)iminomethyl)-L-ornithine on Newcrom R1 HPLC column

May 16, 2018
Separation of N2-D-Gluconoyl-N5-((D-gluconoylamino)iminomethyl)-L-ornithine on Newcrom R1 HPLC column

N2-D-Gluconoyl-N5-((D-gluconoylamino)iminomethyl)-L-ornithine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.