Methyl salicylate

Methyl salicylate structural formula

CAS Number119-36-8
Molecular FormulaC8H8O3
Molecular Weight152.149
  • Methyl salicylate
  • Methyl 2-hydroxybenzoate
  • Benzoic acid, 2-hydroxy-, methyl ester
  • 119-36-8
  • Benzoic acid, 2-hydroxy-, methyl ester
  • Methyl 2-hydroxybenzoate
  • 2-Carbomethoxyphenol
  • PredaLure
  • 4-10-00-00143
  • 2-(Methoxycarbonyl)phenol
  • 2-Hydroxybenzoic acid methyl ester
  • 2-Hydroxybenzoic acid, methyl ester
  • Analgit
  • Anthrapole ND
  • Exagien
  • Flucarmit
  • Methyl o-hydroxybenzoate
  • Methylsalicylat
  • NSC 8204
  • o-Hydroxybenzoic acid methyl ester
  • salicilato de metilo
  • Salicylate de methyle
  • Salicylic acid, methyl ester
  • Betula Lenta
  • BRN 0971516
  • Caswell No. 577
  • EINECS 204-317-7
  • EPA Pesticide Chemical Code 076601
  • FEMA No. 2745
  • FEMA Number 2745
  • Gaultheria oil, artificial
  • Gaultheriaoel
  • Synthetic wintergreen oil
  • Wintergreen oil, synthetic
  • Wintergruenoel
  • Methylester kyseliny salicylove
  • Metylester kyseliny salicylove
  • Betula oil
  • FEMA 2745
  • Gaultheria oil
  • Methyl ester 2-hydroxy-benzoic acid
  • Methyl salicylate, 8CI
  • Natural wintergreen oil
  • O-Hydroxybenzoic acid, methyl ester
  • Oil of wintergreen
  • Spicewood Oil
  • Sweet birch oil
  • Teaberry oil
  • 648434-07-5
  • 8022-86-4
  • 8024-54-2


Separation of Methyl salicylate on Newcrom R1 HPLC column

February 16, 2018
Separation of Methyl salicylate on Newcrom C18 HPLC column

Methyl salicylate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Methyl salicylate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.