Linolenic acid

Linolenic acid structural formula

CAS Number463-40-1
Molecular FormulaC18H30O2
Molecular Weight278.437
  • Linolenic acid
  • (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid
  • 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)-
  • 463-40-1
  • (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid
  • 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)-
  • (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid
  • (all-Z)-9,12,15-Octadecatrienoic acid
  • (Z,Z,Z)-9,12,15-Octadecatrienoic acid
  • (Z,Z,Z)-Octadeca-9,12,15-trienoic acid
  • 9,12,15-all-cis-Octadecatrienoic acid
  • 9,12,15-Octadecatrienoic acid, (Z,Z,Z)-
  • 9-cis,12-cis,15-cis-Octadecatrienoic acid
  • 9Z,12Z,15Z-Octadecatrienoic acid
  • Acide linolenique
  • acido linolenico, bruto
  • all-cis-9,12,15-Octadecatrienoic acid
  • cis,cis,cis-9,12,15-Octadecatrienoic acid
  • cis-9,cis-12,cis-15-Octadecatrienoic acid
  • cis-?9,12,15-Octadecatrienoic acid
  • Linolensaure
  • ?-Linolenic acid
  • EINECS 207-334-8
  • Linolenate
  • NSC 2042
  • cis-delta9,12,15-Octadecatrienoic acid
  • UNII-0RBV727H71
  • (9,12,15)-linolenate
  • (9,12,15)-linolenic acid
  • (9Z,12Z,15Z)-Octadecatrienoate
  • (9Z,12Z,15Z)-Octadecatrienoic acid
  • (Z,Z,Z)-9,12,15-Octadecatrienoate
  • 9,12,15-Octadecatrienoate
  • 9-cis,12-cis,15-cis-Octadecatrienoate
  • ALA
  • All-cis-9,12,15-Octadecatrienoate
  • Industrene 120
  • a-Linolenate
  • a-Linolenic acid
  • all-cis-9,12,15-octadecatrienoic acid
  • alpha-Linolenic acid
  • cis,cis,cis-9,12,15-Octadecatrienoate
  • cis-9,12,15-Octadecatrienoate
  • cis-9,12,15-Octadecatrienoic acid
  • cis-Delta(9,12,15)-octadecatrienoic acid


Separation of Linolenic acid on Newcrom R1 HPLC column

February 19, 2018
Separation of Linolenic acid on Newcrom C18 HPLC column

Linolenic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Linolenic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.