HPLC Determination of Cromolyn Sodium(Sodium cromoglycate) on Newcrom BH Column

Separation type: Liquid Chromatography Mixed-mode

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High Performance Liquid Chromatography (HPLC) Method for Cromolyn sodium

Cromolyn sodium is a medication used to manage bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis. Cromolyn sodium can be retained in HPLC with a Newcrom BH mixed-mode column using a mobile phase of acetonitrile (ACN) and water and Sulfuric Acid (H2SO4) buffer allowing the use of a UV detector at 240 nm.



Column Newcrom BH, 4.6x150 mm,  100A
Mobile Phase MeCN/H2O - 35/65%
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV 240nm


Class of Compounds Drug
Analyzing Compounds Cromolyn sodium (Sodium cromoglycate)
Application Analytes:
Cromolyn sodium (Sodium cromoglycate)