gamma-Guanidinobutyric acid

gamma-Guanidinobutyric acid structural formula

CAS Number463-00-3
Molecular FormulaC5H11N3O2
Molecular Weight145.163
InChI KeyTUHVEAJXIMEOSA-UHFFFAOYSA-N
LogP-0.695
Synonyms
  • gamma-Guanidinobutyric acid
  • 4-[(Diaminomethylidene)amino]butanoic acid
  • Butanoic acid, 4-[(diaminomethylene)amino]-
  • 463-00-3
  • EINECS 207-331-1
  • NSC 521717
  • UNII-15ADP48O8Q
  • 4-(Carbamimidamido)butanoate
  • 4-(Carbamimidamido)butanoic acid
  • 4-Guanidinobutanoate
  • 4-Guanidinobutyrate
  • 4-Guanidinobutyric acid
  • 4-[(diaminomethylidene)amino]butanoic acid
  • gamma-Guanidinobutyrate
  • 4-guanidinobutanoic acid
  • 4-guanidinobutanoic acid zwitterion
  • 4-(diaminomethylideneamino)butanoic acid

Applications:

Separation of gamma-Guanidinobutyric acid on Newcrom R1 HPLC column

May 16, 2018
Separation of gamma-Guanidinobutyric acid on Newcrom R1 HPLC column

gamma-Guanidinobutyric acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
gamma-Guanidinobutyric acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.