Echothiophate structural formula

CAS Number513-10-0
Molecular FormulaC9H23INO3PS
Molecular Weight383.231
  • Echothiophate
  • 2-[(Diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethan-1-aminium iodide
  • Ethanaminium, 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-, iodide (1:1)
  • 513-10-0
  • Ammonium, (2-(O,O-diethylphosphorothio)ethyl)trimethyl-, iodide
  • N-(2-(Diethoxyphosphinylthio)ethyl)trimethylammonium iodide
  • S-(2-Dimethylaminoethyl)-O.O-diethylphosphorothioate methiodide
  • Echodide
  • Ecostigmini jodidum
  • EINECS 208-152-1
  • S-Ester of (2-mercaptoethyl)trimethylammonium iodide with O,O-diethyl phosphorothioate
  • (2-Mercaptoethyl)trimethylammonium iodide S-ester with O,O-diethyl phosphorothioate
  • Phospholine iodide
  • 2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid
  • Ecothiopati iodidum
  • Iodure d'ecothiopate
  • Ioduro de ecotiopato
  • (2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate
  • 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethylethanaminium iodide
  • 2-diethoxy-phosphinylthioethyl-trimethylammonium iodide
  • N-(2-(diethoxyphosphinylthio)ethyl)trimethylammonium iodide
  • O,O-diethyl S-2-trimethylammonium ethylphosphonothiolate iodide
  • S-(2-(N,N,N-trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide
  • S-(2-dimethylaminoethyl)-O,O-diethylphosphorothioate methiodide
  • S-beta-dimethylaminoethyl-O,O-diethylthionophosphate methiodide
  • diethoxyphosphinylthiocholine iodide
  • diethoxyphosphoryl-thiocholine iodide
  • ecothiophate iodide
  • ecothiopate iodide


Separation of Echothiophate on Newcrom R1 HPLC column

February 16, 2018
Separation of Echothiophate on Newcrom C18 HPLC column

Echothiophate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.