Chloroacetyl chloride

Chloroacetyl chloride structural formula

CAS Number79-04-9
Molecular FormulaC2H2Cl2O
Molecular Weight112.941
InChI KeyVGCXGMAHQTYDJK-UHFFFAOYSA-N
LogP0.718
Synonyms
  • Chloroacetyl chloride
  • Acetyl chloride, 2-chloro-
  • 79-04-9
  • Acetyl chloride, chloro-
  • Acetyl chloride, 2-chloro-
  • Chloracetyl chloride
  • Chloracetylchlorid
  • Chloroacetic acid chloride
  • Chloroacetic chloride
  • Chloroethanoyl chloride
  • Chlorure de chloroacetyle
  • cloruro de cloroacetilo
  • Monochloroacetyl chloride
  • UN 1752
  • BRN 0605439
  • EINECS 201-171-6
  • Chlorid kyseliny chloroctove
  • Chlorure de chloracetyle
  • UNII-K5UML06YUO
  • 1256778-77-4

Applications:

Separation of Chloroacetyl chloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Chloroacetyl chloride on Newcrom C18 HPLC column

Chloroacetyl chloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Chloroacetyl chloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.