Benzeneacetic acid, 2,5-dihydroxy-

Benzeneacetic acid, 2,5-dihydroxy- structural formula

CAS Number451-13-8
Molecular FormulaC8H8O4
Molecular Weight168.148
InChI KeyIGMNYECMUMZDDF-UHFFFAOYSA-N
LogP0.86
Synonyms
  • Benzeneacetic acid, 2,5-dihydroxy-
  • (2,5-Dihydroxyphenyl)acetic acid
  • 451-13-8
  • 4-10-00-01506
  • BRN 2692860
  • 2,5-Dihydroxybenzeneacetic acid
  • 2,5-Dihydroxyphenylacetic acid
  • EINECS 207-192-7
  • Homogentisinic acid
  • NSC 88940
  • UNII-NP8UE6VF08
  • (2,5-dihydroxyphenyl)-Acetate
  • (2,5-dihydroxyphenyl)-Acetic acid
  • 2,5-Dihydroxy-a-toluate
  • 2,5-Dihydroxy-a-toluic acid
  • 2,5-Dihydroxy-alpha-toluate
  • 2,5-Dihydroxy-alpha-toluic acid
  • 2,5-Dihydroxy-benzeneacetate
  • 2,5-Dihydroxy-benzeneacetic acid
  • 2-(2,5-dihydroxyphenyl)acetic acid
  • 2-(2,5-dihydroxyphenyl)ethanoic acid
  • Alcapton
  • Homogentisate
  • Homogentisate acid
  • Homogentisinate
  • Homogentisinic acid
  • Melanic acid

Applications:

Separation of Benzeneacetic acid, 2,5-dihydroxy- on Newcrom R1 HPLC column

February 16, 2018
Separation of Benzeneacetic acid, 2,5-dihydroxy- on Newcrom C18 HPLC column

Benzeneacetic acid, 2,5-dihydroxy- can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Benzeneacetic acid, 2,5-dihydroxy-
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.