Antimycin A3

Antimycin A3 structural formula

CAS Number522-70-3
Molecular FormulaC26H36N2O9
Molecular Weight520.579
InChI KeyPVEVXUMVNWSNIG-PDPGNHKXSA-N
LogP3.46
Synonyms
  • Antimycin A3
  • (2R,3S,6S,7R,8R)-8-Butyl-3-(3-formamido-2-hydroxybenzamido)-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate (non-preferred name)
  • 522-70-3
  • Blastomycin
  • EINECS 208-335-6
  • NSC 58239
  • UNII-7JMI3P2Y5R

Applications:

Separation of Antimycin A3 on Newcrom R1 HPLC column

February 19, 2018
Separation of Antimycin A3 on Newcrom C18 HPLC column

Antimycin A3 can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Antimycin A3
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.