Abamectin B1a

Abamectin B1a structural formula

CAS Number65195-55-3
Molecular FormulaC48H72O14
Molecular Weight873.091
InChI KeyRRZXIRBKKLTSOM-XPNPUAGNSA-N
LogP4.83
Synonyms
  • Abamectin B1a
  • (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-Butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
  • 65195-55-3
  • Avermectin A1a, 5-O-demethyl-
  • Antibiotic C 076B1a
  • Antibiotic C 076A1a, 5-O-demethyl-
  • Avermectin B1a
  • Caswell No. 063AB
  • 5-O-Demethylavermectin A1a
  • EINECS 265-610-3
  • Abamectin komponente B1a
  • Abamectina
  • Abamectine
  • UNII-K54ZMM929K
  • abamectin component B1a
  • 355401-08-0

Applications:

Separation of Abamectin B1a on Newcrom R1 HPLC column

May 16, 2018
Separation of Abamectin B1a on Newcrom R1 HPLC column

Abamectin B1a can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Abamectin B1a
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.