Sorbitol and saccharin are two sugar substitutes used in food and drinks. Separation of sorbitol and saccharin was achieved on a Primesep N HILIC column using acetonitrile/water with ammonium formate. Compounds were monitored by combination of UV and ELSD. Method is compatible with LC/MS detection.
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.Select options