Sorbitol and saccharin are two sugar substitutes used in food and drinks. Separation of sorbitol and saccharin was achieved on a Primesep N HILIC column using acetonitrile/water with ammonium formate. Compounds were monitored by combination of UV and ELSD. Method is compatible with LC/MS detection.
The Primesep family of mixed-mode columns offer a wide variety of stationary phases with an unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service which is available for all customers. Ask about our special custom LC-phases tailored for specific separations.Select options