Cysteine-S-sulfate (SSC) is produced by reaction of inorganic sulfite and cystine by a as-yet-unknown pathway, and is a very potent NMDA-receptor antagonist. Cysteine-S-sulfate is a very polar molecule with one basic group, one carboxylic group and one sulfate group. It is retained by Primesep SB column by combination of strong anion-exchange mechanism and weak reversed-phase mechanism. Compound can be monitored by LC/MS, ELSD, Corona or UV detectors. This HPLC method can be adopted as generic approach for analysis of acidic and hydrophobic drugs.
The Primesep family of mixed-mode columns offer a wide variety of stationary phases with an unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service which is available for all customers. Ask about our special custom LC-phases tailored for specific separations.
Select options© SIELC Technologies. 2002 - 2023
Address: 804 Seton Court, Wheeling, IL USA 60090
Tel: (847) 229-2629 | Fax: (847) 655-6079
Sales, Refund and Returns Policy
Email: mail@sielc.com | Sitemap