2-Methylpropanoic acid

2-Methylpropanoic acid structural formula

CAS Number79-31-2
Molecular FormulaC4H8O2
Molecular Weight88.107
InChI KeyKQNPFQTWMSNSAP-UHFFFAOYSA-N
LogP0.94
Synonyms
  • 2-Methylpropanoic acid
  • Propanoic acid, 2-methyl-
  • 79-31-2
  • 4-02-00-00843
  • Propanoic acid, 2-methyl-
  • 2-Methylpropionic acid
  • Acide isobutyrique
  • acido isobutirico
  • Dimethylacetic acid
  • i-Butyric acid
  • Isobutanoic acid
  • ISOBUTTERSAEURE
  • Isobuttersaure
  • isobutyric acid
  • iso-Butyric acid
  • Isopropylformic acid
  • NSC 62780
  • Propionic acid, 2-methyl-
  • UN 2529
  • ?-Methylpropanoic acid
  • ?-Methylpropionic acid
  • Acetic acid, dimethyl-
  • BRN 0635770
  • Caswell No. 503AA
  • Cenex RP b2
  • EINECS 201-195-7
  • EPA Pesticide Chemical Code 101502
  • FEMA No. 2222
  • Tenox IBP-2
  • Tenox IBP-2 Grain Pr.
  • Kyselina isomaselna
  • UNII-8LL210O1U0
  • 2,2-dimethylacetic acid
  • 2-Methylpropanoate
  • 2-Methylpropionate
  • 2-Methylpropionsaeure
  • Dimethylacetate
  • Iso-Butyrate
  • Isopropylformate
  • a-Methylpropanoate
  • a-Methylpropanoic acid
  • a-Methylpropionate
  • a-Methylpropionic acid
  • alpha-Methylpropanoate
  • alpha-Methylpropionate
  • alpha-isobutyric acid
  • alpha-methylpropanoic acid
  • alpha-methylpropionic acid
  • i-Butyrate
  • iso-C3H7COOH

Applications:

Separation of 2-Methylpropanoic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of 2-Methylpropanoic acid on Newcrom C18 HPLC column

2-Methylpropanoic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2-Methylpropanoic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.