2-Methylbutanoic acid

2-Methylbutanoic acid structural formula

CAS Number116-53-0
Molecular FormulaC5H10O2
Molecular Weight102.134
InChI KeyWLAMNBDJUVNPJU-UHFFFAOYSA-N
LogP1.18
Synonyms
  • 2-Methylbutanoic acid
  • Butanoic acid, 2-methyl-
  • 116-53-0
  • 2-Methylbutyric acid
  • 4-02-00-00889
  • Butanoic acid, 2-methyl-
  • (.+-.)-2-Methylbutanoic acid
  • (.+-.)-2-METHYLBUTYRIC ACID
  • (.+-.)-Methylethylacetic acid
  • (.+-.)-?-Methylbutyric acid
  • (+/-)-2-Methyl Butyric Acid
  • 2-Ethylpropanoic acid
  • 2-Methylbuttersaure
  • 2-Methyl-n-butyric acid
  • Acide 2-methylbutyrique
  • acido 2-metilbutirico
  • Active valeric acid
  • BUTANOIC ACID, 2-METHYL-, (+)-
  • Butyric acid, 2-methyl-
  • Butyric acid, ?-methyl-
  • DL-2-Methylbutanoic acid
  • DL-2-Methylbutyric acid
  • DL-?-Methylbutyric acid
  • Ethylmethylacetic acid
  • METHYL-2-BUTYRIC ACID
  • Methylethylacetic acid
  • NSC 7304
  • ?-Methylbutyric acid
  • ?-Methyl-n-butyric acid
  • BRN 1098537
  • EINECS 204-145-2
  • EINECS 209-982-7
  • FEMA No. 2695
  • Valeric acid, active
  • UNII-PX7ZNN5GXK
  • (+/-)-2-Methylbutyrate
  • (+/-)-2-Methylbutyric acid
  • 2-Ethylpropionate
  • 2-Ethylpropionic acid
  • 2-Methyl Butyrate
  • 2-Methyl Butyric acid
  • 2-Methylbutanoate
  • 2-methybutyric acid
  • D-2-Methyl Butyrate
  • D-2-Methyl Butyric acid
  • DL-2-Methy Butyrate
  • DL-2-Methy Butyric acid
  • DL-2-Methylbutyrate
  • Ethylmethylacetate
  • alpha-methyl butyric acid
  • alpha-methylbutyric acid
  • butane-2-carboxylic acid
  • 600-07-7

Applications:

Separation of 2-Methylbutanoic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of 2-Methylbutanoic acid on Newcrom C18 HPLC column

2-Methylbutanoic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2-Methylbutanoic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.