1-Bromopropane

1-Bromopropane structural formula

CAS Number106-94-5
Molecular FormulaC3H7Br
Molecular Weight122.993
InChI KeyCYNYIHKIEHGYOZ-UHFFFAOYSA-N
LogP2.10
Synonyms
  • 1-Bromopropane
  • Propane, 1-bromo-
  • 106-94-5
  • Propane, 1-bromo-
  • 1-bromopropano
  • 1-Brompropan
  • 1-Propyl bromide
  • Ascusol MC
  • N-PROPYL BROMIDE
  • Propyl bromide
  • UN 2344
  • EINECS 203-445-0
  • UNII-Y9746DNE68

Applications:

HPLC Method for Analysis of 1-Bromopropane on Newcrom R1 Column

August 2, 2022

 

Separation type: Liquid Chromatography Reverse Phase
 

 

 

High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Bromopropane

 

1-Bromopropane, or n-propylbromide, is a very popular industrial solvent with a wide variety of applications, including in aerosolized adhesives, asphalt production, aviation maintenance, and in synthetic fiber production. 1-Bromopropane can be retained and analyzed on a Newcrom R1 reverse-phase column using a simple isocratic analytical method with a mobile phase consisting of just Acetonitrile (MeCN) and water (with no ionic modifier). This analysis method can be UV detected at 210 nm with high resolution and peak symmetry.

Condition

Column Newcrom R1, 4.6×150 mm, 3 µm, 100A
Mobile Phase MeCN – 55%
Buffer None
Flow Rate 1.0 ml/min
Detection UV 210 nm

 

Description

Class of Compounds
Alkyl bromides
Analyzing Compounds 1-Bromopropane

Application Column

Newcrom R1

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A

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Application Analytes:
1-Bromopropane
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of 1-Bromopropane on Newcrom R1 HPLC column

February 16, 2018
Separation of 1-Bromopropane on Newcrom C18 HPLC column

1-Bromopropane can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
1-Bromopropane
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.