Nizatidine

Nizatidine

CAS Number76963-41-2
Molecular FormulaC12H21N5O2S2
Molecular Weight331.450
InChI KeySGXXNSQHWDMGGP-UHFFFAOYSA-N
LogP0.235
Synonyms
  • Nizatidine
  • N1-{2-[({2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)sulfanyl]ethyl}-N'1-methyl-2-nitroethene-1,1-diamine
  • 1,1-Ethenediamine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-methyl-2-nitro-
  • 76963-41-2
  • 1,1-Ethenediamine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-methyl-2-nitro-
  • 1,1-Ethenediamine, N'-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N-methyl-2-nitro-
  • Calmaxid
  • Cronizat
  • Distaxid
  • Gastrax
  • N-[2-[2-[(Dimethylamino)methyl]-1H-imidazole-1-yl]-5-nitrophenyl]methanone
  • Naxidine
  • Nizaxid
  • Zanizal
  • BRN 4846056
  • N-(2-(((2-((Dimethylamino)methyl)-4-thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine
  • 1,1-Ethenediamine, N-(2-(((2-((dimethylamino)methyl)-4-thiazoly)methyl)thio)ethyl)-N'-methyl-2-nitro-
  • N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamin
  • Ulcosol
  • Antizid
  • Galitidin
  • Panaxid
  • Splendil ER
  • Axid AR
  • Nizatidina
  • Nizatidinum
  • UNII-P41PML4GHR
  • N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine

Applications:

HPLC Method for Analysis of Nizatidine

May 10, 2016

2




Nizatidine is a competitive and reversible histamine H2-receptor antagonist. It is used for the treatment of duodenal ulcers, acid-peptic disease and heartburn. In some rare instances, the drug can cause a clinically apparent acute injury of the liver. Primesep 200 which is a reverse phase column, contains embedded acidic ionizable groups and can retain Nizatidine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Nizatidine
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.