Naled

Naled structural formula

CAS Number300-76-5
Molecular FormulaC4H7Br2Cl2O4P
Molecular Weight380.780
InChI KeyBUYMVQAILCEWRR-UHFFFAOYSA-N
LogP1.38
Synonyms
  • Naled
  • 1,2-Dibromo-2,2-dichloroethyl dimethyl phosphate
  • Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester
  • 300-76-5
  • Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester
  • 1,2-Dibromo-2,2-dichloroethyl dimethyl phosphate
  • Bromchlophos
  • Dibrom 8 Emulsive
  • Dibromfos
  • Dimethyl 1,2-dibromo-2,2-dichloroethyl phosphate
  • Flibol Ex
  • Fosbrom
  • O,O-Dimethyl O-(1,2-dibromo-2,2-dichloroethyl) phosphate
  • Trumpet
  • Arthodibrom
  • BRN 2049930
  • Caswell No. 586
  • O,O-Dimethyl O-2,2-dichloro-1,2-dibromoethyl phosphate
  • O,O-Dimethyl-O-(1,2-dibromo-2,2-dichloroethyl)phosphate
  • EINECS 206-098-3
  • EPA Pesticide Chemical Code 034401
  • Ethanol, 1,2-dibromo-2,2-dichloro-, dimethyl phosphate
  • Nikabrom
  • Ortho-dibrom
  • Orthodibromo
  • Fosforan O-1,2-dwubromo-2,2-dwuchloroetylo-O,O-dwumetylowy
  • O-(1,2-Dibrom-2,2-dichlor-aethyl)-O,O-dimethyl-phosphat
  • O-(1,2-Dibromo-2,2-dicloro-etil)-O,O-dimetil-fosfato
  • O-(1,2-Dibroom-2,2-dichloor-ethyl)-O,O-dimethyl-fosfaat
  • O,O-Dimethyl-O-(1,2-dibrom-2,2-dichlor-aethyl)-phosphat
  • Phosphate de O,O-dimethyle et de O-(1,2-dibromo-2,2-dichlorethyle)
  • UNII-PAM1AI9KU1
  • O-(1,2-dibromo-2,2-dichloroethyl)-O,O-dimethyl phosphate
  • dimethyl-1,2-dibromo-2,2-dichloroethyl phosphate
  • phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester
  • 53095-31-1

Applications:

Analysis of Naled on Primesep and Obelisc Mixed-Mode HPLC Columns

August 24, 2015

 

Naled is an organophosphate insecticide that shows relatively low toxicity. While home use has been discontinued, naled is still used in public mosquito eradication programs. Naled can be reduced to dichlorvos, which the EURL (European Union Reference Laboratory), included as a target pesticide for the EUPT-CF9 a proficiency test for cereals and feedingstuff that require muli-residue methods. Primesep B2 and Obelisc R were used to retain naled and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing naled, other organophosphate insecticides, and dozens of other pesticides.

 

Condition 1
Column Primesep B2, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm

 

Condition 2
Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm

 

 

Description
Class of Compounds
  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Naled

 

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options

Primesep B2

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Naled
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Analysis of Naled on Obelisc R Column

August 10, 2015

Naled is an organophosphate insecticide that shows relatively low toxicity. While home use has been discontinued, naled is still used in public mosquito eradication programs. Naled can be reduced to dichlorvos, which the EURL included as a target pesticide for the EUPT-CF9. Obelisc R was used to retain naled and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing naled and other organophosphate insecticides.

Condition
Column Obelisc R, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN – 40%
Buffer AmFm pH 3.0- 20 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm

 

 

Description
Class of Compounds
  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Naled

 

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
Naled
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.