Captan

Captan structural formula

CAS Number133-06-2
Molecular FormulaC9H8Cl3NO2S
Molecular Weight300.580
InChI KeyLDVVMCZRFWMZSG-UHFFFAOYSA-N
LogP2.80
Synonyms
  • Captan
  • 2-[(Trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
  • 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-
  • 133-06-2
  • Merpan
  • 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-
  • 1,2,3,6-Tetrahydro-N-(trichloromethylthio)phthalimide
  • 3a,4,7,7a-Tetrahydro-2-((trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione
  • 3a,4,7,7a-Tetrahydro-2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione
  • 4-Cyclohexene-1,2-dicarboximide, N-[(trichloromethyl)thio]-
  • Aacaptan
  • Amercide
  • Bangtan
  • Bangton
  • Buvisild K
  • Captadin
  • Captan [1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-]
  • Captane
  • Esso fungicide 406
  • Fungus Ban Type II
  • Glyodex 37-22
  • Hexacap
  • IH-Isoindole-1,3(2H)-dione,3a,4,7,7a-tetrahydro-2 -[(trichloromethyl)thio]
  • ISOINDOLE(1H)-1,3(2H)-DIONE, 3A,4,7,7A-TETRAHYDRO-2-[(TRICHLOROMETHYL)THIO]-
  • Kaptazor
  • Malipur
  • Micro-Chek 12
  • N-[(Trichloromethyl)thio]-4-cyclohexene-1,2-dicarboximide
  • N-[(Trichloromethyl)thio]tetrahydrophthalimide
  • N-[(Trichloromethyl)thio]-Δ4-tetrahydrophthalimide
  • Neracid
  • NSC 36726
  • N-Trichloromethylmercapto-4-cyclohexene-1,2-dicarboximide
  • N-Trichloromethylthio-3a,4,7,7a-tetrahydrophthalimide
  • N-Trichloromethylthio-4-cyclohexene-1,2-dicarboximide
  • N-trichloromethylthio-4-cyclohexene-1,2-dicarboxyimide
  • Orthocide
  • Orthocide 406
  • Orthocide 50
  • Orthocide 7.5
  • Orthocide 75
  • Orthocide 75W
  • Orthocide 83
  • Orthocide 83RP
  • Orthocide S 50
  • Osocide
  • Radocaptan
  • Rallis captaf
  • Stauffer captan
  • Trimegol
  • Vancide 89RE
  • Vangard K
  • Venturin
  • Zenecal
  • Agrosol S
  • Agrox 2-way and 3-way
  • Bean Seed Protectant
  • BRN 0023177
  • Captancapteneet 26,538
  • Captanex
  • Caswell No. 159
  • 4-Cyclohexene-1,2-dicarboxylic acid, imide, N(trichloromethylthio)-
  • EINECS 205-087-0
  • EPA Pesticide Chemical Code 081301
  • Glyodex 3722
  • Granox PFM
  • Gustafson captan 30-DD
  • Isotox Seed Treater D
  • Isotox Seed Treater F
  • Micro-check 12
  • NCI-C00077
  • N-(Trichloromethylmercapto)-delta(sup 4)-tetrahydrophthalimide
  • N-Trichloromethylthio-cis-delta(sup 4)-cyclohexene-1,2-dicarboximide
  • Trichloromethylthio-1,2,5,6-tetrahydrophthalamide
  • N-((Trichloromethyl)thio)tetrahydrophthalimide
  • Vancide P-75
  • Vanicide
  • Vondcaptan
  • LE Captane
  • N-(Trichlor-methylthio)-phthalimid
  • Trichlormethylthioamid kyseliny 1,2,3,6-tetrahydroftalove
  • UNII-EOL5G26Q9F
  • 3a,4,7,7a-tetrahydro-N-(trichloromethanesulphenyl)phthalimide
  • ENT 26,538
  • N-(trichloromethylmercapto)-Delta(4)-tetrahydrophthalimide
  • N-trichloromethylthio-3a,4,7,7a-tetrahydrophthalimide
  • N-trichloromethylthiocyclohex-4-ene-1,2-dicarboximide
  • SR 406
  • SR406
  • 120528-25-8
  • 1321-42-2
  • 37335-15-2

Applications:

HPLC Separation of Captan on Obelisc R and Primesep 100 Columns

September 14, 2015

 

 

Captan is a fungicide that is typically combined with other pesticides. It is in the class of fungicides called phthalimide, and is used on a number of vegetables and ornamental plants. Captan reduces infections on the surface of plant material improving their appearance. The EURL-SRM (European Union Reference Laboratory – Single Residue Methods) included captan in a list of pesticides difficult to analyze by traditional multiresidue methods. We separated and analyzed captan using two mixed-mode columns with different modes of separation. Obelisc R has a long hydrophobic chain and multiple ion-pairing groups, and Primesep 100 contains acidic ion-pairing groups. Method is LC/MS compatible and can be use on many different pesticides.

 

Condition 1

Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 25-70%
Buffer Gradient AmAc pH 3.0- 30-60 mM
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Condition 2

Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%
Buffer Gradient AmAc pH 3.0- 20-60 mM
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Condition 3

Column Primesep 100, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%
Buffer Gradient AmAc pH 3.0- 20-60 mM
Flow Rate 0.4 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
 Insecticide, Pesticide, Hydrophobic, Ionizable
Analyzing Compounds Captan

 

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Captan

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Captan Retention on Obelisc R HPLC Column

August 24, 2015
Captan is a phthalimide fungicide which is typically used as a component in industrial pesticide mixtures. The EURL included a QuEChERS (Quick, Easy, Cheap, Rugged, and Safe) method for captan as a target pesticide for EUPT-SRM. Obelisc R was used to retain captan and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing captan.

Condition 

Column Obelisc R, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN – 45%
Buffer AmFm pH 3.0- 40 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm

 

 

Description

Class of Compounds
 Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Captan

 

Application Column

Obelisc R

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
Captan
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Captan Separation on Obelisc and Primesep Mixed-Mode HPLC Columns

August 24, 2015

 

Captan is a phthalimide fungicide which is typically used as a component in industrial pesticide mixtures. The EURL included a QuEChERS (Quick, Easy, Cheap, Rugged, and Safe) method for captan as a target pesticide for EUPT-SRM. Obelisc R was used to retain captan and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups while Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing captan and dozens of other pesticides.

 

Condition 1

Column Primesep B2, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm

 

Condition 2

Column Obelisc R, 2.1×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm

 

 

Description

Class of Compounds
 Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Captan

 

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options

Primesep B2

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Captan

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.