CAS Number | 13922-41-3 |
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Molecular Formula | C10H9BO2 |
Molecular Weight | 171.99 |
InChI Key | HUMMCEUVDBVXTQ-UHFFFAOYSA-N |
Synonyms |
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Applications:
HPLC Separation of Aromatic Boronic Acids on Primesep P
July 8, 2011
Boronic acid is alkyl, or aryl substituted, boric acid. Boronic acid can form complexes with sugars, amines, and amino acids. Four aromatic boronic acids were separated on a Primesep P mixed-mode reversed-phase cation-exchange column. Primesep P column also has an aromatic fragment which provides pi-pi interaction. Compounds can be monitored by UV, ELSD, CAD and LC/MS. Various mobile phases can be employed for HPLC analysis of boronic acids.
Column | Primesep P, 4.6×150 mm, 5 µm, 100A |
Mobile Phase | MeCN/H2O |
Buffer | H2SO4 |
Flow Rate | 1.0 ml/min |
Detection | UV 270 nm |
Class of Compounds |
Drug, Acid, Hydrophobic, Ionizable |
Analyzing Compounds | Chlorohenyl-4-boronic acid, Naphtalene-1-boronic acid, Biphenyl-4-boronic acid, 4-(1-naphthyl)phenylboronic acid |
Application Column
Primesep P
Column Diameter: 4.6 mm
Column Length: 250 mm
Particle Size: 5 µm
Pore Size: 100 A
4-Chlorophenylboronic acid
Biphenyl-4-boronic acid
Naphthalene-1-boronic acid