Biphenyl-4-boronic acid

Biphenyl-4-boronic acid

CAS Number5122-94-1
Molecular FormulaC12H11BO2
Molecular Weight198.030
InChI KeyXPEIJWZLPWNNOK-UHFFFAOYSA-N
LogP2.91
Synonyms
  • 1,1'-Biphenyl-4-yl-boronic acid
  • [1,1'-Biphenyl]-4-ylboronic acid
  • Boronic acid, B-[1,1'-biphenyl]-4-yl-
  • 5122-94-1
  • 4-Biphenylboronic acid
  • (1,1'-Biphenyl)-4-ylboronic acid

Applications:

HPLC Separation of Aromatic Boronic Acids on Primesep P

July 8, 2011

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Boronic acid is alkyl, or aryl substituted, boric acid. Boronic acid can form complexes with sugars, amines, and amino acids. Four aromatic boronic acids were separated on a Primesep P mixed-mode reversed-phase cation-exchange column. Primesep P column also has an aromatic fragment which provides pi-pi interaction. Compounds can be monitored by UV, ELSD, CAD and LC/MS. Various mobile phases can be employed for HPLC analysis of boronic acids.

 

 

Condition

Column Primesep P, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer H2SO4
Flow Rate 1.0 ml/min
Detection UV 270 nm

 

Description

Class of Compounds
Drug, Acid, Hydrophobic, Ionizable
Analyzing Compounds Chlorohenyl-4-boronic acid, Naphtalene-1-boronic acid, Biphenyl-4-boronic acid, 4-(1-naphthyl)phenylboronic acid

 

Application Column

Primesep P

Column Diameter: 4.6 mm
Column Length: 250 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
4-(1-naphthyl)phenylboronic acid
4-Chlorophenylboronic acid
Biphenyl-4-boronic acid
Naphthalene-1-boronic acid

Application Detection:
UV Detection
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