Sodium cholate

Sodium cholate structural formula

CAS Number361-09-1
Molecular FormulaC24H39NaO5
Molecular Weight430.562
InChI KeyNRHMKIHPTBHXPF-TUJRSCDTSA-M
LogP2.02
Synonyms
  • Sodium cholate
  • Sodium (3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-oate
  • Cholan-24-oic acid, 3,7,12-trihydroxy-, sodium salt, (3alpha,5beta,7alpha,12alpha)- (1:1)
  • 361-09-1
  • Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3?,5?,7?,12?)-
  • (3?,5?,7?,12?)-3,7,12-Trihydroxycholan-24-oic acid monosodium salt
  • Cholan-24-oic acid, 3,7,12-trihydroxy-, sodium salt (1:1), (3?,5?,7?,12?)-
  • Cholate de sodium
  • Cholic acid sodium salt
  • Cholic acid, monosodium salt
  • colato de sodio
  • Natriumcholat
  • Sodium cholic acid
  • Cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3-alpha,5-beta,7-alpha,12-alpha)-
  • EINECS 206-643-5
  • Trihydroxy 3-7-12 cholanate de Na
  • UNII-NU3Y4CCH8Z
  • 32500-01-9

Applications:

Separation of Sodium cholate on Newcrom R1 HPLC column

May 16, 2018
Separation of Sodium cholate on Newcrom R1 HPLC column

Sodium cholate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Sodium cholate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.