Protirelin

Protirelin structural formula

CAS Number24305-27-9
Molecular FormulaC16H22N6O4
Molecular Weight362.391
InChI KeyXNSAINXGIQZQOO-SRVKXCTJSA-N
LogP-2.46
Synonyms
  • Protirelin
  • 5-Oxo-L-prolyl-L-histidyl-L-prolinamide
  • L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-
  • 24305-27-9
  • L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-
  • (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2
  • Abbott 38579
  • Antepan
  • Lopremone
  • L-Pyroglutamyl-L-histidyl-L-prolinamide
  • L-Pyroglutamyl-L-histidyl-L-proline amide
  • protirelina
  • protireline
  • Relefact TRH
  • Rifathyroin
  • Rifotironin
  • Ro 8-6270/9
  • Stimu TSH
  • Synthetic thyrotropin-releasing factor
  • Synthetic thyrotropin-releasing hormone
  • Synthetic TRF
  • Synthetic TRH
  • Synthetic TSH-releasing factor
  • Synthetic TSH-releasing hormone
  • Thypinone
  • Thyrefact
  • Thyroid releasing hormone
  • Thyroid-stimulating hormone-releasing factor
  • Thyroliberin
  • Thyrotropic hormone-releasing factor
  • Thyrotropic hormone-releasing hormone
  • Thyrotropic releasing hormone
  • Thyrotropic-releasing factor
  • Thyrotropin-releasing factor
  • Thyrotropin-releasing hormone
  • TSH-releasing factor
  • TSH-releasing hormone
  • EINECS 246-143-4
  • L-Pyroglutamyl-L-histidyl-L-prolineamide
  • Thyrothropin relasing hormone
  • Thyrotropin releasing hormone
  • Thyrel TRH
  • Protirelinum
  • UNII-5Y5F15120W

Applications:

Separation of Protirelin on Newcrom R1 HPLC column

February 16, 2018
Separation of Protirelin on Newcrom C18 HPLC column

Protirelin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Protirelin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.