Penicillin VK

Penicillin VK structural formula

CAS Number132-98-9
Molecular FormulaC16H17KN2O5S
Molecular Weight388.481
InChI KeyHCTVWSOKIJULET-LQDWTQKMSA-M
LogP0.966
Synonyms
  • Penicillin VK
  • Potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, potassium salt, (2S,5R,6R)- (1:1)
  • 132-98-9
  • Antibiocin
  • Apsin VK
  • Arcacil
  • Arcasin
  • Aspin VK
  • Beepen-VK
  • Betapen-VK
  • Calciopen K
  • V-Cil-K
  • V-Cillin K
  • Cliacil
  • Compocillin-VK
  • Distakaps V-K
  • Dowpen V-K
  • EINECS 205-086-5
  • Isocillin
  • Ispenoral
  • Kavepenin
  • Ledercillin VK
  • Megacillin oral
  • Monopotassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
  • Oracil-VK
  • Ospeneff
  • Pedipen
  • Penagen
  • Penapar VK
  • Pencompren
  • Penicillin V potassium
  • Penicillin V potassium salt
  • Penicillin potassium phenoxymethyl
  • Pen-Vee K
  • Penvikal
  • Pfizerpen VK
  • D-alpha-Phenoxymethylpenicillinate K salt
  • Potassium penicillin V
  • Potassium penicillin V salt
  • Potassium phenoxymethyl penicillin
  • Potassium phenoxymethylpenicillin
  • Primcillin
  • Qidpen VK
  • Robicillin VK
  • Rocillin-VK
  • Roscopenin
  • SK-Penicillin VK
  • Stabillin VK syrup 125
  • Stabillin VK syrup 62.5
  • Sumapen VK
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2 -phenoxyacetamido)-, monopotassium salt
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(( phenoxyacetyl)amino)-, monopotassium salt, (2S-(2alpha,5alpha,6beta))-
  • Uticillin VK
  • Veetids
  • Penapar-VK
  • Veetids '125'
  • Veetids '250'
  • Veetids '500'
  • UNII-146T0TU1JB
  • Phenoxymethylpenicillin potassium
  • 8059-73-2

Applications:

Separation of Penicillin VK on Newcrom R1 HPLC column

February 19, 2018
Separation of Penicillin VK on Newcrom C18 HPLC column

Penicillin VK can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Penicillin VK
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.