Leptophos

Leptophos structural formula

CAS Number21609-90-5
Molecular FormulaC13H10BrCl2O2PS
Molecular Weight412.060
InChI KeyCVRALZAYCYJELZ-UHFFFAOYSA-N
LogP6.31
Synonyms
  • Leptophos
  • O-(4-Bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate
  • Phosphonothioic acid, P-phenyl-, O-(4-bromo-2,5-dichlorophenyl) O-methyl ester
  • 21609-90-5
  • O-(4-Bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate
  • Caswell No. 525B
  • O-(2,5-Dichloro-4-bromophenyl) O-methyl phenylthiophosphonate
  • EINECS 244-472-8
  • EPA Pesticide Chemical Code 525300
  • O-Methyl O-2,5-dichloro-4-bromophenyl phenylthiophosphonate
  • O-Methyl-O-(4-bromo-2,5-dichlorophenyl)phenyl thiophosphonate
  • Oleophosvel
  • Phenylphosphonothioic acid O-(4-bromo-2,5-dichlorophenyl) O-methyl ester
  • Phosphonothioic acid, phenyl-, O-(4-bromo-2,5-dichlorophenyl) O-methyl ester
  • Phosvel
  • Velsicol 506
  • Velsicol VCS 506
  • (+-)-Leptophos
  • UNII-C45E8FUG3Z
  • 73270-49-2

Applications:

Separation of Leptophos on Newcrom R1 HPLC column

February 16, 2018
Separation of Leptophos on Newcrom C18 HPLC column

Leptophos can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Leptophos
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.