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Perfluoroalkyl acids (PFAAs) such as Perfluorobutyric acid, Perfluorononanoic acid and Perfluorooctylsulfonic acid are contaminants that have increasingly been found in groundwater and drinking water systems.
Perfluoroalkyl acids (PFAAs) are also strong surfactants that have been used industrially, in the production of fluoropolymers, but they are also present as residual impurities in a wide range of polymeric consumer products e.g. used to impart water and stain repellency in textiles, papers, and boards.
We were able to separate Perfluoroalkyl acids (PFAAs) in HPLC on Newcrom A mixed-mode column using a mobile phase of acetonitrile (ACN), and water with Ammonium Formate buffer. This separation can be monitored with ELSD, CAD detection techniques.
| Column | Newcom A, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN – 40% |
| Buffer | AmFm pH 3.0 – 50 mM |
| Flow Rate | 1.0 ml/min |
| Detection | CAD |
| Class of Compounds | Perfluoroalkyl acids |
| Analyzing Compounds | Perfluorobutyric acid, Perfluorononanoic acid, Perfluorooctylsulfonic acid |
Application Column
Newcrom A
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsPerfluorooctanoic acid (PFOA)
Perfluorooctylsulfonic acid (PFAS)
