HPLC Method For Analysis Of 2,4,6-Trichloroanisole on Newcrom R1 Column

Separation type: Liquid Chromatography Reverse Phase


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High Performance Liquid Chromatography (HPLC) Method for Analysis of 2,4,6-Trichloroanisole

2,4,6-Trichloroanisole (TCA) is a fungal metabolite of 2,4,6-Trichlorophenol, which is a popular fungicide. TCA also has a distinct musty smell that is most evident when wines develop tainted corks. TCA can be retained and analyzed on a Newcrom R1 mixed-mode column using an isocratic analytical method with a simple mobile phase of water, Acetonitrile (MeCN), and no buffer. This analysis method can be UV detected at 210 nm.

Condition
Column Newcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 70/30%
Buffer None
Flow Rate 1.0 ml/min
Detection UV, 210 nm

 

Description
Class of Compounds
 Haloanisole
Analyzing Compounds 2,4,6-Trichloroanisole

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2,4,6-Trichloroanisole
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.