Separation type: Liquid Chromatography Mixed-mode
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High Performance Liquid Chromatography (HPLC) Method for Cromolyn sodium
Cromolyn sodium is a medication used to manage bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis. Cromolyn sodium can be retained in HPLC with a Newcrom BH mixed-mode column using a mobile phase of acetonitrile (ACN) and water and Sulfuric Acid (H2SO4) buffer allowing the use of a UV detector at 240 nm.
Column | Newcrom BH, 4.6×150 mm, 100A |
Mobile Phase | MeCN/H2O – 35/65% |
Buffer | H2SO4 – 0.1% |
Flow Rate | 1.0 ml/min |
Detection | UV 240nm |
Class of Compounds | Drug |
Analyzing Compounds | Cromolyn sodium (Sodium cromoglycate) |
Application Column
Newcrom B
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsNewcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options