HPLC Determination of 6-methyl-5-hepten-2-one on Newcrom R1 Column

HPLC Determination of 6-methyl-5-hepten-2-one
Sulcatone is a ketone used as a mosquito attractant. It is a volatile oil component found in
citrus. It can be retained on a Newcrom R1reverse-phase column with a mobile phase of acetonitrile (ACN) and water with sulfuric acid (H2SO4) buffer. The analytical method is MS-compatible and can also use UV detection at 200nm.


Column Newcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer H2SO4 – 0.1 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm



Class of Compounds
Hydrophobic, Mosquito attractant
Analyzing Compounds 6-methyl-5-hepten-2-one


Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.