Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. We estimated that limit of detection is about 2 ppm for this compounds with this method. The peak of polyhexanide fractionated on several peaks due to difference in length of the polymer components.
|Column||PEI , 4.6x250 mm, 5 µm, 100A|
|Mobile Phase||MeCN/H2O - 40/60%|
|Buffer||AmFm pH 3.0- 20 mM|
|Flow Rate||0.5 ml/min|
|Detection||UV, 236 nm|
|Class of Compounds||Polymer, Hydrophilic, Ionizable, Antiseptic, Disinfectant|
|Analyzing Compounds||Polyhexanide (PHMB)|