Cyclobenzaprine hydrochloride

Cyclobenzaprine hydrochloride structural formula

CAS Number6202-23-9
Molecular FormulaC20H22ClN
Molecular Weight311.851
InChI KeyVXEAYBOGHINOKW-UHFFFAOYSA-N
LogP4.50
Synonyms
  • Cyclobenzaprine hydrochloride
  • 3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine--hydrogen chloride (1/1)
  • 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
  • 6202-23-9
  • 10,11delta-Amitriptyline hydrochloride
  • 5-(3-Dimethylaminopropylidene)-5H-dibenzo-(a,d)cycloheptene hydrochloride
  • N,N-Dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine hydrochloride
  • EINECS 228-264-4
  • Flexeril
  • Flexiban
  • MK 130 hydrochloride
  • NSC 169900
  • NSC 173379
  • NSC 78206
  • Proheptatrien monohydrochloride
  • Proheptatriene hydrochloride
  • Proheptatriene monohydrochloride
  • Cycloflex
  • Novo-Cycloprine
  • Tensodox
  • UNII-0VE05JYS2P
  • Tabradol
  • Multi-Relax
  • Yurelax
  • N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Delta(5,gamma)-propylamine hydrochloride
  • cyclobenzaprine HCl

Applications:

Separation of Cyclobenzaprine hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Cyclobenzaprine hydrochloride on Newcrom C18 HPLC column

Cyclobenzaprine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Cyclobenzaprine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.