Chloramphenicol succinate

Chloramphenicol succinate structural formula

CAS Number3544-94-3
Molecular FormulaC15H16Cl2N2O8
Molecular Weight423.201
InChI KeyLIRCDOVJWUGTMW-ZWNOBZJWSA-N
LogP0.988
Synonyms
  • Chloramphenicol succinate
  • 4-{[(2R,3R)-2-(2,2-Dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propyl]oxy}-4-oxobutanoic acid
  • Butanedioic acid, mono[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester
  • 3544-94-3
  • 4-13-00-02756
  • BRN 3228488
  • Chloramphenicol acid succinate
  • Chloramphenicol hemisuccinate
  • Chloramphenicol hydrogen succinate
  • Chloramphenicol monosuccinate
  • Chloromycetin succinate
  • Chronicin foam
  • EINECS 222-590-0
  • Kemicetine succinate
  • Levomycetin hemisuccinate
  • Levomycetin succinate
  • Paraxin succinate
  • Succinato de cloranfenicol
  • UNII-ZCX619U9A1

Applications:

Separation of Chloramphenicol succinate on Newcrom R1 HPLC column

May 16, 2018
Separation of Chloramphenicol succinate on Newcrom R1 HPLC column

Chloramphenicol succinate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Chloramphenicol succinate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.