Carteolol hydrochloride

Carteolol hydrochloride structural formula

CAS Number51781-21-6
Molecular FormulaC16H25ClN2O3
Molecular Weight328.840
InChI KeyFYBXRCFPOTXTJF-UHFFFAOYSA-N
LogP1.53
Synonyms
  • Carteolol hydrochloride
  • 5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one--hydrogen chloride (1/1)
  • 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, hydrochloride (1:1)
  • 51781-21-6
  • Abbott-43326
  • 5-(3-tert-Butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyril hydrochloride
  • Carbonolol
  • Cartrol
  • EINECS 257-415-7
  • Endak hydrochloride
  • Endak mite
  • 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril hydrochloride
  • Mikelan
  • NSC 300906
  • Ocupress
  • Abbott 43326
  • Arteoptic
  • UNII-4797W6I0T4
  • 5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1H)-quinolinone hydrochloride
  • 5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydrocarbostyril monohydrochloride
  • 5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1H)-chinolinon-hydrochlorid
  • Carteolol HCl
  • N-tert-butyl-2-hydroxy-3-[(2-oxo-1,2,3,4-tetrahydroquinolin-5-yl)oxy]propan-1-aminium chloride

Applications:

Separation of Carteolol hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Carteolol hydrochloride on Newcrom C18 HPLC column

Carteolol hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Carteolol hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.