Praziquantel is an anthelmintic drug effective against flatworms. The drug is used to treat diseases in humans, mammals, and fish. Praziquantel and related impurities can be analyzed by reversed-phase chromatography according to the USP, United States Pharmacopeia, manuscript. It requires a reversed-phase HPLC column, classified as L1. This method was developed on the Legacy L1 column and can be used for analysis of various molecules according to USP.
| Column | Legacy L1, 4.6x150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O - 60/40% |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 210 nm |
| Class of Compounds | Drug, Anthelmintic, Hydrophobic |
| Analyzing Compounds | Praziquantel |
Application Analytes:
USP Methods for the Analysis of Praziquantel using the Legacy L1 Column