Indomethacin

Indomethacin structural formula

CAS Number53-86-1
Molecular FormulaC19H16ClNO4
Molecular Weight357.791
InChI KeyCGIGDMFJXJATDK-UHFFFAOYSA-N
LogP4.27
Synonyms
  • Indomethacin
  • [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
  • 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
  • 53-86-1
  • 5-22-05-00239
  • 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
  • [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
  • 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
  • 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
  • 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
  • 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
  • 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
  • 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid
  • 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
  • Artracin
  • Artrinovo
  • Artrivia
  • Bonidin
  • Bonidon Gel
  • Chibro-Amuno
  • Chrono-Indicid
  • Chrono-Indocid 75
  • Confortid
  • Dolcidium
  • Dolcidium PL
  • Dolovin
  • Durametacin
  • Elmetacin
  • Idomethine
  • Imbrilon
  • Indacin
  • Indocid
  • Indocin
  • Indocollyre
  • Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-
  • Indomecol
  • Indomed
  • Indomee
  • indometacin
  • indometacina
  • Indometacine
  • Indomethacine
  • Indomethine
  • Indomod
  • Indonol
  • Indo-Phlogont
  • Indoptic
  • Indoptol
  • Indo-Rectolmin
  • Indorektal
  • IndoRich
  • Indo-Tablinen
  • Indoxen
  • Inflazon
  • Infrocin
  • Innamit
  • Inteban
  • Inteban SP
  • Metacen
  • Metartril
  • Methazine
  • Metindol
  • Mezolin
  • Mikametan
  • Mobilan
  • N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
  • NSC 77541
  • Reumacide
  • Rheumacin LA
  • Sadoreum
  • Vital Vitacid
  • α-[1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl]acetic acid
  • BRN 0497341
  • N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid
  • (1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid
  • alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid
  • EINECS 200-186-5
  • Indomethacinum
  • Indomethazine
  • NCI-C56144
  • Indocin SR
  • Indo-lemmon
  • 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure
  • 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico
  • Indometacinum
  • Indometacyna
  • Indometicina
  • Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy
  • UNII-XXE1CET956
  • Indomet 140
  • 37242-43-6
  • 503560-73-4
  • 91853-74-6

Applications:

HPLC Method for Analysis of Indomethacin on Primesep 200

May 6, 2016

Chr_1070 Indomethacin is a nonsteroidal anti-inflammatory drug used to reduce pain, fever, and stiffness. It is much stronger and has more side effects than other NSAIDS. Indomethacin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particle columns are available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation of impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Primesep 200

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Indomethacin
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.